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Nakamura, Yusuke
One or more keywords matched the following items that are connected to Nakamura, Yusuke
Item TypeName
Concept C-Reactive Protein
Concept Protein Denaturation
Concept Protein Methyltransferases
Concept Protein Precursors
Concept Protein-Tyrosine Kinases
Concept Protein Binding
Concept Protein Conformation
Concept Protein Processing, Post-Translational
Concept Protein-Arginine N-Methyltransferases
Concept Protein Biosynthesis
Concept rac1 GTP-Binding Protein
Concept Mitogen-Activated Protein Kinases
Concept Oncogene Protein p21(ras)
Concept RNA-Binding Protein EWS
Concept Protein Structure, Tertiary
Concept BRCA1 Protein
Concept Fas Ligand Protein
Concept Receptor Protein-Tyrosine Kinases
Concept Protein Transport
Concept Protein Tyrosine Phosphatases, Non-Receptor
Concept Protein Tyrosine Phosphatases
Concept Protein Folding
Concept HMGB1 Protein
Concept Adaptor Protein Complex 3
Concept Adaptor Protein Complex delta Subunits
Concept Protein Interaction Mapping
Concept Receptors, G-Protein-Coupled
Concept TATA-Binding Protein Associated Factors
Concept Iron Regulatory Protein 1
Concept Mitogen-Activated Protein Kinase 3
Concept rhoA GTP-Binding Protein
Concept Mitogen-Activated Protein Kinase Kinases
Concept BRCA2 Protein
Concept Adenomatous Polyposis Coli Protein
Concept GRB10 Adaptor Protein
Concept Proto-Oncogene Protein c-fli-1
Concept Protein Kinase C
Concept Transmembrane Activator and CAML Interactor Protein
Concept Receptor-Interacting Protein Serine-Threonine Kinase 2
Concept Receptor-Like Protein Tyrosine Phosphatases, Class 3
Concept Protein Phosphatase 1
Concept Ubiquitin-Protein Ligases
Concept Sterol Regulatory Element Binding Protein 1
Concept Inhibitor of Differentiation Protein 2
Concept Protein Interaction Domains and Motifs
Concept Protein Multimerization
Concept MutS Homolog 2 Protein
Concept CDC2 Protein Kinase
Concept Smad7 Protein
Concept Retinoblastoma Protein
Concept Insulin-Like Growth Factor Binding Protein 2
Concept Mitogen-Activated Protein Kinase 1
Concept Calcium-Calmodulin-Dependent Protein Kinases
Concept cdc42 GTP-Binding Protein
Concept JNK Mitogen-Activated Protein Kinases
Concept Transcription Factor 7-Like 2 Protein
Concept Nod2 Signaling Adaptor Protein
Concept RNA-Binding Protein FUS
Concept Protein Interaction Maps
Concept Early Growth Response Protein 2
Concept Protein Stability
Concept Wnt4 Protein
Concept Tumor Suppressor Protein p53
Concept Protein Isoforms
Concept Protein Array Analysis
Concept GTP-Binding Protein alpha Subunits, G12-G13
Concept Protein Kinase Inhibitors
Concept p38 Mitogen-Activated Protein Kinases
Concept bcl-2 Homologous Antagonist-Killer Protein
Academic Article The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
Academic Article Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.
Academic Article Ring finger protein 43 as a new target for cancer immunotherapy.
Academic Article Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
Academic Article Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
Academic Article A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction.
Academic Article Genome-wide detection and characterization of positive selection in human populations.
Academic Article Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia.
Academic Article Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
Academic Article Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis.
Academic Article Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.
Academic Article Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma.
Academic Article Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.
Academic Article Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients.
Academic Article The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.
Academic Article Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors.
Academic Article Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke.
Academic Article PADI4 polymorphism predisposes male smokers to rheumatoid arthritis.
Academic Article Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility.
Academic Article Possible involvement of NEDD4 in keloid formation; its critical role in fibroblast proliferation and collagen production.
Academic Article Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.
Academic Article Genome-wide association meta-analysis identifies new endometriosis risk loci.
Academic Article Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis: case-control studies.
Academic Article Multiple loci are associated with white blood cell phenotypes.
Academic Article Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
Academic Article Pharmacogenomics of tamoxifen: roles of drug metabolizing enzymes and transporters.
Academic Article A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese.
Academic Article A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.
Academic Article Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.
Academic Article ORAI1 genetic polymorphisms associated with the susceptibility of atopic dermatitis in Japanese and Taiwanese populations.
Academic Article Induction of tenascin-C by tumor-specific EWS-ETS fusion genes.
Academic Article Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells.
Academic Article Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.
Academic Article Catalog of 300 SNPs in 23 genes encoding G-protein coupled receptors.
Academic Article Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
Academic Article Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma.
Academic Article Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis.
Academic Article Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53.
Academic Article Identification of 156 novel SNPs in 29 genes encoding G-protein coupled receptors.
Academic Article Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.
Academic Article Regulation of protein Citrullination through p53/PADI4 network in DNA damage response.
Academic Article Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells.
Academic Article Common variants in CASP3 confer susceptibility to Kawasaki disease.
Academic Article Identification of 45 novel SNPs in the 83-kb region containing peptidylarginine deiminase types 1 and 3 loci on chromosomal band 1p36.13.
Academic Article Identification of 20 novel SNPs in the guanine nucleotide binding protein alpha 12 gene locus.
Academic Article Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.
Academic Article Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
Academic Article C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage.
Academic Article Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.
Academic Article A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese.
Academic Article Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
Academic Article Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker.
Academic Article MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells.
Academic Article Association of the RIP2 gene with childhood atopic asthma.
Academic Article Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma.
Academic Article Targeted serum glycoproteomics for the discovery of lung cancer-associated glycosylation disorders using lectin-coupled ProteinChip arrays.
Academic Article Overexpression of the potential kinase serine/ threonine/tyrosine kinase 1 (STYK 1) in castration-resistant prostate cancer.
Academic Article Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus.
Academic Article Phosphorylation and activation of cell division cycle associated 5 by mitogen-activated protein kinase play a crucial role in human lung carcinogenesis.
Academic Article Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells.
Academic Article Polypeptide N-acetylgalactosaminyltransferase 6 disrupts mammary acinar morphogenesis through O-glycosylation of fibronectin.
Academic Article TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
Academic Article Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.
Academic Article Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism.
Academic Article Involvement of the tubulin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells.
Academic Article The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
Academic Article Cancer peptide vaccine therapy developed from oncoantigens identified through genome-wide expression profile analysis for bladder cancer.
Academic Article Critical function for nuclear envelope protein TMEM209 in human pulmonary carcinogenesis.
Academic Article Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.
Academic Article Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6).
Academic Article Cyclin K as a direct transcriptional target of the p53 tumor suppressor.
Academic Article Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53.
Academic Article Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.
Academic Article Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease.
Academic Article SMYD3 interacts with HTLV-1 Tax and regulates subcellular localization of Tax.
Academic Article Crosstalk of EDA-A2/XEDAR in the p53 signaling pathway.
Academic Article New gene functions in megakaryopoiesis and platelet formation.
Academic Article The Xq22 inversion breakpoint interrupted a novel Ras-like GTPase gene in a patient with Duchenne muscular dystrophy and profound mental retardation.
Academic Article Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell.
Academic Article Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis.
Academic Article Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells.
Academic Article Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer.
Academic Article Activation of CDCA1-KNTC2, members of centromere protein complex, involved in pulmonary carcinogenesis.
Academic Article The neuromedin U-growth hormone secretagogue receptor 1b/neurotensin receptor 1 oncogenic signaling pathway as a therapeutic target for lung cancer.
Academic Article ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.
Academic Article Predictive biomarkers for the outcome of vaccination of five therapeutic epitope peptides for colorectal cancer.
Academic Article Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis.
Academic Article A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer.
Academic Article Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839).
Academic Article Identification of membrane-type matrix metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in human colorectal cancers.
Academic Article Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR.
Academic Article Aberrant laminin beta3 isoforms downstream of EWS-ETS fusion genes in Ewing family tumors.
Academic Article Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125).
Academic Article WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck.
Academic Article Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family.
Academic Article p53RDL1 regulates p53-dependent apoptosis.
Academic Article Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity.
Academic Article Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
Academic Article Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.
Academic Article Identification of promiscuous KIF20A long peptides bearing both CD4+ and CD8+ T-cell epitopes: KIF20A-specific CD4+ T-cell immunity in patients with malignant tumor.
Academic Article Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis.
Academic Article High-density SNP map of human ITR, a gene associated with vascular remodeling.
Academic Article Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis.
Academic Article Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention.
Academic Article A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C.
Academic Article SNPs in BRAP associated with risk of myocardial infarction in Asian populations.
Academic Article Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema.
Academic Article Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker.
Academic Article Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.
Academic Article CLCA2 as a p53-inducible senescence mediator.
Academic Article Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells.
Academic Article Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells.
Academic Article Catalog of 178 variations in the Japanese population among eight human genes encoding G protein-coupled receptors (GPCRs).
Academic Article A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.
Academic Article Therapeutic potential of antibodies against FZD 10, a cell-surface protein, for synovial sarcomas.
Academic Article A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease.
Academic Article Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis.
Academic Article Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.
Academic Article Hypoxia-inducible protein 2 (HIG2), a novel diagnostic marker for renal cell carcinoma and potential target for molecular therapy.
Academic Article WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
Academic Article Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma.
Academic Article hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53.
Academic Article ESE-3, an Ets family transcription factor, is up-regulated in cellular senescence.
Academic Article The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3.
Academic Article EGR2 induces apoptosis in various cancer cell lines by direct transactivation of BNIP3L and BAK.
Academic Article Identification of immunoglobulin superfamily 11 (IGSF11) as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas.
Academic Article Coding SNP in tenascin-C Fn-III-D domain associates with adult asthma.
Academic Article A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
Academic Article Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation.
Academic Article RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation.
Academic Article Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1.
Academic Article Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
Academic Article Inhibition of tumor growth through suppression of angiogenesis by brain-specific angiogenesis inhibitor 1 gene transfer in murine renal cell carcinoma.
Academic Article Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
Academic Article The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination.
Academic Article Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer.
Academic Article Radioimmunotherapy of human synovial sarcoma using a monoclonal antibody against FZD10.
Academic Article Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay.
Academic Article Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.
Academic Article MRG-binding protein contributes to colorectal cancer development.
Academic Article Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma.
Academic Article Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population.
Academic Article Identification of an HLA-A2-restricted epitope peptide derived from hypoxia-inducible protein 2 (HIG2).
Academic Article Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians.
Academic Article Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer.
Academic Article Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.
Academic Article Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity.
Academic Article Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B.
Academic Article ANLN plays a critical role in human lung carcinogenesis through the activation of RHOA and by involvement in the phosphoinositide 3-kinase/AKT pathway.
Academic Article A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population.
Academic Article Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.
Academic Article Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses.
Academic Article Critical roles of T-LAK cell-originated protein kinase in cytokinesis.
Academic Article The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
Academic Article Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1alpha and nuclear factor kappaB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure.
Academic Article Identification of TOMM34, which shows elevated expression in the majority of human colon cancers, as a novel drug target.
Academic Article VAV3 mediates resistance to breast cancer endocrine therapy.
Academic Article A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
Academic Article Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.
Academic Article Adenovirus-mediated p53AIP1 gene transfer as a new strategy for treatment of p53-resistant tumors.
Academic Article Detection of novel cancer-testis antigen-specific T-cell responses in TIL, regional lymph nodes, and PBL in patients with esophageal squamous cell carcinoma.
Academic Article Enhanced expression of EHMT2 is involved in the proliferation of cancer cells through negative regulation of SIAH1.
Academic Article A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability.
Academic Article Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
Academic Article Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.
Academic Article Identification of NOL8, a nucleolar protein containing an RNA recognition motif (RRM), which was overexpressed in diffuse-type gastric cancer.
Academic Article The p53 family member genes are involved in the Notch signal pathway.
Academic Article Identification of semaphorin3B as a direct target of p53.
Academic Article Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.
Academic Article Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis.
Academic Article SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation.
Academic Article The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).
Academic Article Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers.
Academic Article Heterozygous TGFBR2 mutations in Marfan syndrome.
Academic Article SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
Academic Article Critical roles of non-histone protein lysine methylation in human tumorigenesis.
Academic Article Identification of human leukocyte antigen-A24-restricted epitope peptides derived from gene products upregulated in lung and esophageal cancers as novel targets for immunotherapy.
Academic Article Dysregulation of AKT Pathway by SMYD2-Mediated Lysine Methylation on PTEN.
Academic Article Identification of the interleukin 4 receptor alpha gene as a direct target for p73.
Academic Article Isolation of a novel gene, CABC1, encoding a mitochondrial protein that is highly homologous to yeast activity of bc1 complex.
Academic Article PDZ-binding kinase/T-LAK cell-originated protein kinase, a putative cancer/testis antigen with an oncogenic activity in breast cancer.
Academic Article TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis.
Academic Article Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor.
Academic Article Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes.
Academic Article Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome.
Academic Article DDX31 regulates the p53-HDM2 pathway and rRNA gene transcription through its interaction with NPM1 in renal cell carcinomas.
Academic Article SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells.
Academic Article The NSD family of protein methyltransferases in human cancer.
Academic Article PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents.
Academic Article T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia.
Academic Article Regulation of iron homeostasis by the p53-ISCU pathway.
Academic Article PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP.
Academic Article SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells.
Academic Article Overexpressed P-cadherin/CDH3 promotes motility of pancreatic cancer cells by interacting with p120ctn and activating rho-family GTPases.
Academic Article Characterization of SEZ6L2 cell-surface protein as a novel prognostic marker for lung cancer.
Academic Article Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
Academic Article Elevated expression of protein regulator of cytokinesis 1, involved in the growth of breast cancer cells.
Academic Article Mutated G-protein-coupled receptor GPR10 is responsible for the hyperphagia/dyslipidaemia/obesity locus of Dmo1 in the OLETF rat.
Academic Article Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.
Academic Article Understanding the functional significance of ghrelin processing and degradation.
Academic Article Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.
Academic Article Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway.
Academic Article Proteomic characterization of ovarian cancers identifying annexin-A4, phosphoserine aminotransferase, cellular retinoic acid-binding protein 2, and serpin B5 as histology-specific biomarkers.
Academic Article Radioimmunotherapy of solid tumors targeting a cell-surface protein, FZD10: therapeutic efficacy largely depends on radiosensitivity.
Academic Article Retraction: Epstein-Barr virus-encoded latent membrane protein 1 activates ß-catenin signaling in B lymphocytes.
Academic Article Retraction. Cloning and expression of soluble recombinant human esophageal cancer-related gene 4 protein and its inhibitory effect on tumor growth in vitro and in vivo in esophageal carcinoma.
Academic Article Toxoplasma gondii exploits UHRF1 and induces host cell cycle arrest at G2 to enable its proliferation.
Academic Article Megakaryocyte potentiating factor as a tumor marker of malignant pleural mesothelioma: evaluation in comparison with mesothelin.
Academic Article Herpes simplex virus-induced, death receptor-dependent apoptosis and regression of transplanted human cancers.
Academic Article Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity.
Academic Article Dysregulation of protein methyltransferases in human cancer: An emerging target class for anticancer therapy.
Academic Article Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
Academic Article Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With ERBB Alterations.
Academic Article Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.
Academic Article Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.
Academic Article Automethylation of SUV39H2, an oncogenic histone lysine methyltransferase, regulates its binding affinity to substrate proteins.
Academic Article Anti-myeloma activity of MELK inhibitor OTS167: effects on drug-resistant myeloma cells and putative myeloma stem cell replenishment of malignant plasma cells.
Academic Article p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1.
Academic Article The forkhead box M1 transcription factor as a candidate of target for anti-cancer immunotherapy.
Academic Article Effective induction of cytotoxic T cells recognizing an epitope peptide derived from hypoxia-inducible protein 2 (HIG2) in patients with metastatic renal cell carcinoma.
Academic Article T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer.
Academic Article Mutations in the gene encoding KIAA1199 protein, an inner-ear protein expressed in Deiters' cells and the fibrocytes, as the cause of nonsyndromic hearing loss.
Academic Article HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres.
Academic Article TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer.
Academic Article WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer.
Academic Article GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.
Academic Article Expression of hypoxia-inducible protein 2 in renal cell carcinoma: A promising candidate for molecular targeting therapy.
Academic Article Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention.
Academic Article Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small-cell lung cancer cells.
Academic Article Multiple therapeutic peptide vaccines for patients with advanced gastric cancer.
Academic Article The Transcriptional Landscape of p53 Signalling Pathway.
Academic Article Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization.
Academic Article Protein methyltransferases and demethylases dictate CD8+ T-cell exclusion in squamous cell carcinoma of the head and neck.
Academic Article A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors.
Academic Article Critical roles of protein methyltransferases and demethylases in the regulation of embryonic stem cell fate.
Academic Article The role of protein methyltransferases as potential novel therapeutic targets in squamous cell carcinoma of the head and neck.
Academic Article Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility.
Academic Article Corrigendum to "The role of protein methyltransferases as potential novel therapeutic targets in squamous cell carcinoma of the head and neck" [Oral Oncol. 81 (2018) 100-108].
Academic Article Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma.
Academic Article MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
Academic Article Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.
Academic Article Clinical significance of gene mutation in ctDNA analysis for hormone receptor-positive metastatic breast cancer.
Academic Article Clinicopathologic significance of protein lysine methyltransferases in cancer.
Academic Article High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo.
Academic Article Anti-cancer immunotherapy using cancer-derived multiple epitope-peptides cocktail vaccination clinical studies in patients with refractory/persistent disease of uterine cervical cancer and ovarian cancer [phase 2].
Academic Article Application of targeted nanopore sequencing for the screening and determination of structural variants in patients with Lynch syndrome.
Concept Forkhead Box Protein O1
Concept Enhancer of Zeste Homolog 2 Protein
Concept Suppressor of Cytokine Signaling 1 Protein
Concept ORAI1 Protein
Concept MutL Protein Homolog 1
Concept Tumor Protein p73
Concept Forkhead Box Protein M1
Concept Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
Concept NLR Family, Pyrin Domain-Containing 3 Protein
Concept Tumor Necrosis Factor alpha-Induced Protein 3
Concept Jagged-1 Protein
Concept Jagged-2 Protein
Concept F-Box-WD Repeat-Containing Protein 7
Concept Homeobox Protein Nkx-2.5
Concept Nedd4 Ubiquitin Protein Ligases
Concept Protein Kinase C-theta
Concept Centromere Protein A
Concept Protein-Arginine Deiminases
Concept Ataxia Telangiectasia Mutated Proteins
Concept 3-Phosphoinositide-Dependent Protein Kinases
Concept Death-Associated Protein Kinases
Concept Myotonin-Protein Kinase
Concept Protein Aggregates
Academic Article SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck.
Search Criteria
  • Ataxia Telangiectasia Mutated Proteins